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        Chorionic Gonadotrophin
        CAS No.: 9002-61-3 (Gonadotrophic hormone)

        Short Description:

        Source: Extracted from the urine of healthy pregnant women
        Function and use: For women, it can promote the maturation and ovulation of follicles, and maintain the function of the corpus luteum. For men, it can stimulate the development of Leydig cells, increase androgen secretion, promote testicular descent and the development of male secondary sexual characteristics. Combined with urinary gonadotropin, it can simulate the physiological peak of luteinizing hormone and induce ovulation. Clinically, chorionic gonadotropin is still the drug of choice for the treatment of menstrual disorders, anovulatory infertility, threatened abortion and habitual live birth, cryptorchidism, and male sexual dysfunction.

        Chorionic?Gonadotrophin-Pharmacopoeia?Standard:?BP/EP


        Product Detail

        Product Tags

        CAS No.: 9002-61-3
        Complies with CP2020, USP43, BP2022, EP10.0

        Specification

        Chorionic Gonadotrophin
        Source Pregnant woman?urine
        Process description Chorionic gonadotrophin is a dry preparation of placental glycoproteins?which have luteinising activity. It is extracted from the urine of pregnant women.
        Productionrequirements This product should be extracted from healthy human urine. The production process should conform with the requirements of current?version of?Good Manufacturing Practice. It needs to undergo appropriate technological methods for virus safety control during the production process, so that any viruses such as hepatitis virus, human immunodeficiency virus, etc. can be removed or inactivated.

        Pharmacopoeia standard

        CP

        EP/BP

        Character

        White or yellowish-White, amorphous powder.?Soluble?in water and insoluble in ethanol, acetone or ether. White or yellowish-white, amorphous powder.?Soluble in water.

        Identification

        When administered to immature rats as prescribed in the assay, it causes an increase in the mass of the seminal vesicles and of the prostate gland. When administered to immature rats as prescribed in the assay, it causes an increase in the mass of the seminal vesicles and of the prostate gland.

        Test

        Residual solvent Conform with regulation _________
        Water ≤5% maximum 5.0 per cent.
        Estrogen Should not be positive _________
        Abnormal toxicity Conform with regulation _________
        Bacterial endotoxin ≤0.01EU?per IU of HCG Less than 0.02 IU per IU of HCG

        Potency

        Chorionic gonadotrophin bioassay Not less than 4500 IU/mg Not?less than 2500 IU/mg

        Microbial limit

        TAMC
        TYMC

        Virus

        Hbs Ag Should be negative(10mg/ml) _________
        HCV antibodies _________
        HIV I+II _________

        Storage

        In an airtight, tamper-proof container, protected from light. Preserved at cold place. In an airtight, tamper-proof container, protected from light at a temperature of 2 °C to 8 °C.

        Category

        Gonadotropin drugs

        Preparation

        Chorionic Gonadotrophin for injection

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